The fresco in the dome of Florence cathedral is the largest in the world, covering nearly an acre of surface (39,000sq2). It was begun by the celebrated artists and biographer, Giorgio Vasari, in 1572, but completed after his death in 1574 by Federico Zuccari. The main subject of the fresco is the Last Judgment, which occupies one of the eight sections of the octagonal dome. Each the remaining seven sections represents the seven virtues, the seven gifts of the Holy Spirit, and the seven deadly sins (with particularly entertaining hell imagery!) Buona visione!