On April 26, 1478, Giuliano de’ Medici lay dead on the pavement of Florence cathedral with 19 stab wounds serving as testimony to the vicious attack that he had just suffered. Had his assassins succeeded in eliminating his older brother, Lorenzo “il Magnifico” de’ Medici, that day as well, the history of western Europe, and the world for that matter, would have been drastically altered. This episode will examine the protagonists, motivation, and plot behind one of history’s greatest conspiracies.